Biotechnology
Senior Scientist
Enzymology, Plant-microbe interactions, Functional genomics
+91-1894-233339 Ext. 356; +91-9418830880
15-07-1980
PhD

My research interests and long term goals are: (1) to identify enzymes with novel functions and exploit them in healthcare and agriculture industry and (2) to understand the mechanisms of genetic resistance in crops against bacterial and fungal pathogens at the molecular and biochemical levels and exploit this information for crop improvement.

 

1. "Ramanujan Fellowship” by SCIENCE & ENGINEERING RESEARCH BOARD, DST, GOI in 2017.

2. "Shimamoto Travel Award" to attend the IS-MPMI XVII Congress, July 17-21, 2016 in Portland, Oregon, USA.

3. "Start Up Research Grant (Young Scientist)" by SCIENCE & ENGINEERING RESEARCH BOARD, DST, GOI in 2015. 

4. "Travel Grant to attend 20th Penn State Plant Biology Symposium" on May 13-16, 2015 University Park, Pennsylvania, USA. 

5. "Protein Science Young Investigator Travel Grant" from The Protein Society, USA to attend “The Protein Symposium-2013” held at Boston, MA, USA.

6. "Travel grant" from Department of Science and Technology (DST) and perdeim from Indian National Science Academy (INSA), Govt. of India to attend 13th International Botanical Congress at Melbourne, Australia in 2011.

7. Awarded with "CSIR-Senior Research Fellowship” in 2008. 

8. Qualified "CSIR/UGC Test for lectureship (NET)" in Dec 2004 in Life Sciences awarded by Council of Scientific and Industrial Research (CSIR), Govt. of India.

9. Qualified "Graduate aptitude test for engineering (GATE)" with 94.82 percentile in 2004 conducted jointly by the Indian Institute of Science and seven Indian Institutes of Technology.

1. Munaiz, E.D., Martinez, S., Kumar, A., Caicedo, M., Ordas, B. (2020). The Senescence (Stay-Green): an Important Trait to Exploit Crop Residuals for Bioenergy. Energies, 13: 790.

2. Karre, S., Kumar, A., Yogendra, K.N., Kage, U., Kushalappa, A.C., Charron, JB. (2019). HvWRKY23 regulates flavonoid glycoside and hydroxycinnamic acid amide biosynthetic genes in barley to combat Fusarium head blight. Plant Molecular Biology, 100: 591–605.

3. Baghel, M., Nagraja, A., Srivastav, M., Meena, N.K., Kumar, M.S, Kumar, A., Sharma, R.R. (2019). Pleiotropic influences of brassinosteroids on fruit crops- a review. Plant Growth Regulation, 87: 375–388.

4. Kumar, A., Mosa, K., Ji, L., Kage, U., Madalageri, D., Dhokane, D.,Rana, N.P. (2017). Metabolomics assisted biotechnological interventions for developing plant-based functional foods and nutraceuticals. Critical Reviews in Food Science and Nutrition, 58(11):1791-1807. *Corresponding author.

5. Kumar, A., Jansky, S., Halterman, D. (2017). Potato stem cuttings to study Verticillium dahliae infection for resistance breeding and -omics studies. American Journal of Potato Research, 94: 270-274.

6. Karre, S., Kumar, A., Dhokane, D., Kushalappa, A.C. (2016). Metabolo-transcriptome profiling of barley reveals induction of a novel chitin elicitor receptor kinase gene (HvCERK1) conferring resistance against Fusarium graminearum. Plant Molecular Biology, 93: 247-267.

7. Kumar, A., Sharma, M., Bhardwaj, P.K., Singh, D., Kumar, S. (2016). Copper, zinc superoxide dismutase from Caragana jubata: a thermostable enzyme that functions under a broad pH and temperature window. Process Biochemistry, 51: 1434-1444.

8. Kumar, A., Yogendra, K.N., Karre, S., Kushalappa, A.C., Dion, Y., Choo, T.M. (2016). WAX INDUCER1 (HvWIN1) transcription factor regulates free fatty acid biosynthetic genes to reinforce cuticle to resist Fusarium head blight in barley spikelets. Journal of Experimental Botany, 67: 4127-39.

9. Yogendra, K.N., Kumar, A., Sarkar, K., Li, Y., Pushpa, D., Mosa, K., Duggavathi, R., Kushalappa, A.C. (2015). Transcription factor StWRKY1 regulates phenylpropanoid metabolites in potato to resist late blight. Journal of Experimental Botany, 66: 7377-7389. 

10. Kumar, A., Karre, S., Dhokane, D., Kage, U., Hukkeri, S., Kushalappa, A.C. (2015). Real-time quantitative PCR based method for the quantification of fungal biomass to discriminate quantitative resistance in barley and wheat to fusarium head blight. Journal of Cereal Science 64: 16-22.

11. Kage, U., Kumar, A., Dhokane, D., Karre, S., Kushalappa, A.C. (2015). Functional molecular markers in crop improvement. Critical Reviews in Biotechnology, 36: 917-930.

12. Kumar, A., Randhawa, V., Acharya, V., Singh, K., and Kumar, S. (2015). Amino acids flanking the central core of Cu,Zn superoxide dismutase are important in imparting activity after autoclaving. Journal of Biomolecular Structure & Dynamics, 34: 475-485.

13. Kumar, A., Kaachra, A., Bhardwaj, S., Kumar, S. (2014). Copper, zinc superoxide dismutase of Curcuma aromatica is a kinetically stable protein. Process Biochemistry 49: 1288-1296.

14. Kumar, A*., Kage, U., Mosa, K., Dhokane, D. (2014). Metabolomics: a novel tool to bridge phenome to genome under changing climate to ensure food security. Medicinal and Aromatic Plants 3: e154. DOI: 10.4172/2167-0412.1000e154. (Editorial; *Corresponding author).

15. Kumar, A., Dutt. S., Bagler, G., Ahuja, P.S., and Kumar, S. (2012). Engineering a thermo-stable superoxide dismutase functional at sub-zero to >50 °C, which also tolerates autoclaving. Scientific Reports, 2: 387; DOI, 10.1038/srep00387.

16. Bafana, A., Dutt. S., Kumar, A., Kumar, S., and Ahuja, P.S. (2011). The basic and applied aspects of superoxide dismutase. Journal of Molecular Catalysis B: Enzymatic 68:129-138.

17. Ghawana, S., Paul, A., Kumar, H., Kumar, A., Singh, H., Bhardwaj, P.K.,Rani, A., Singh, K., Raizada, J., Singh, R.S., Ahuja, P.S., and Kumar., S. (2011). An RNA isolation system free of Guanidinium salts for isolation of RNA from plant tissues rich in secondary metabolites. BMC Research Notes 4:85.

18. Ganguli, A., Bansal, S., Malik, N., Rana, A. K., and Ghosh, M. (2004). Microbiological Quality and Safety of Two Popularly Consumed Raw, Street Vended Foods in India. Food Science and Biotechnology 13: 417-420.

19. Ghosh, M, Rana, A.K., Bansal, S, and Ganguli, A. (2005). Predictive Microbiology: An Emerging Tool for Assessing Food Safety and Quality. Bioinformatics India 3: 95-99.

1. Kumar, A., Dutt, S., Ahuja, P.S., and Kumar, S. An autoclave stable recombinant Cu/Zn superoxide dismutase with enhanced thermoflexibility (NF0050/2011). Filed in India (Application no. 1031del 2011 dated 11.4.2011).

2. Bhardwaj, P.K., Kumar, A., Kishore, A., Ghawana, S., Rani, A., Singh, K., Singh, H., Singh, R.S., Kumar, H., Sood, P., Dutt, S., Kumar, S., and Ahuja, P.S. Method of cloning stable stress tolerant superoxide dismutase using degenerate primers. US Patent No. US 9212350 B2 (2015/12/15). (Granted).

3. Bhardwaj, P.K., Kumar, A., Kishore, A., Ghawana, S., Rani, A., Singh, K., Singh, H., Singh, R.S., Kumar, H., Sood, P., Dutt, S., Kumar, S., and Ahuja, P.S. Method of cloning stable stress tolerant superoxide dismutase using degenerate primers. European patent Publication no. EP2268661 (Other details: Application no. EP20090727645; PCT no. A2909727645.5; publication date: January 5, 2011).

Technology Transfer: An engineered variant of Cu,Zn SOD with a very unique property of autoclave-stability was developed, patented and the technology for production of enzyme was licensed to M/s PHYTO BIOTECHTM, Kolkata; http://www.phytobiotech.in/superoxide-dismutase.html) (MoU signed on 28th Feb, 2014).

Ph.D. students:

Ashish Dhiman (CSIR/UGC-JRF)

Mahima Chauhan (CSIR/UGC-JRF)

Pratibha Chaudhary (CSIR/UGC-JRF)

Postdocs:

Dr. Pankaj Kumar

*Highly motivated candidates aspiring for a Ph.D. degree or postdoctoral training having independent fellowships are welcome to join my lab.

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