Chemical Technology
Senior Scientist
Organic Chemistry (Natural Product Chemistry)
01894-233339 Ext. 363
02-04-1981
PhD
CV.pdf

 Prospecting natural colours/dyes from the plants of Himalaya, Development of            processes for bioactive/ coloured compounds 

Exploration of undescribed scafolds of bioactive compounds from himalayan plants.

Validation of analytical methods for quantitative/qualitative analysis of plant secondary metabolites, Chemical fingerprinting for the standardization of the medicinal plants /extracts/herbal formulations through analytical techniques.

 Design and synthesis of cognitive enhancers, anti-diabetic and antioxidant agents and their structural activity relationship studies. 


 

 

 

Content of article "Dammarane triterpenoid glycosides in Bacopa monnieri: A review on chemical diversity and bioactivity" selected for front cover page by Phytochemistry, 172,2020.

Dr. P.D. Sethi Annual Award, Certificate of Merit for Best publication “Stability-Indicating HPLC-PDA Method for Determination of Picrosides in HepatoprotectiveIndian Herbal Preparations of Picrorhiza kurroa" 2009

Dr. P.D. Sethi Best Publication Award for “A validated and Densitometric HPTLCMethod for the quantification of Withaferin-A and Withanolide-A in Different Plantparts of Two Morphotypes of Withania somnifera” 2007

Life member of Society of Analytical Scientist

CSIR- Senior Research Fellowship

National Talent Merit Scholarship

HMT Scholistic Award

3rd rank in HPBSE during Matriculation

 

1.    Nitisha Sendri, Shinde Bhagatsing Devidas, Swati Katoch, Vikram Patial,Pamita Bhandari. Copigmentation and UPLC-ESI-MS/MS of anthocyanin in Ipomea nil as potential source of food colorant. Natural Product Research, 2020. https://doi.org/10.1080/14786419.2020.

2.    Pamita Bhandari, Nitisha Sendri, Shinde Bhagatsing Devidas. Dammarane triterpenoid glycosides in Bacopa monnieri: A review on chemical diversity and bioactivity. Phytochemistry, 2020, 172.

3.    Pamita Bhandari, Neeraj Kumar, Kamlesh Kumar Bhutani, Online Antioxidant Activity and Ultra-performance LC-Electrospray Ionization-Quadrupole Time-of-flight Mass Spectrometry for Chemical Fingerprinting of Indian Polyherbal Formulations. Natural Product Research, 2016, 30 (5) 530-535.

4.    Saranjeet Kaur, Pamita Bhandari, K.K. Bhutani, Characterization of bioactive compounds at seedling stage and optimization of seed germination, culture multiplication of Dendrobium nobile lindl.-a study in vitro. International Journal of Advance Research, 2015, 3 (4) 1041-1052. 

5.    Pamita Bhandari, Neeraj Kumar Patel, Rahul P. Gangwal, Abhay T. Sangamwar, Kamlesh Kumar Bhutani, Oleanolic acid-based analogues as NO, TNF-α and IL-1β inhibitors: synthesis, biological evaluation and docking studies. Bioorganic and medicinal chemistry letters, 2014, 24 (17) 4114-4119. 

6.    Pamita Bhandari, Neeraj Kumar Patel, Kamlesh Kumar Bhutani. Synthesis of new heterocyclic lupeol derivatives as nitric oxide and pro-inflammatory cytokineinhibitors, Bioorganic and Medicinal Chemistry Letters, 2014, 24 (15) 3596-3599. 

7.    Rakesh Kumar, Pamita Bhandari, Bikram Singh, P. S. Ahuja. Evaluation of Picrorhiza kurrooa accessions for growth and quality in north western Himalayas. Journal of Medicinal Plants Research, 2012, 6 (13), 2660-2665.

8.    Vivek Sharma, Pamita Bhandari, Bikram Singh, Amita Bhatacharya, Veerubommu Shanmugam. Chitinase Expression Due to Reduction in Fusaric Acid Level in an Antagonistic Trichoderma harzianum S17TH. Indian Journal of Microbiology, 2012, DOI 10.1007/s12088-012-0335-2. 

9.    Pranay Bantawa, Swapan Kumar Ghosh, Pamita Bhandari, Bikram Singh, Partha Deb Ghosh, Paramvir Singh Ahuja, Tapan Kumar Mondal. Micropropagation of an elite line of Picrorhiza scrophulariiflora, Pennell, an endangered high valued medicinal plant of the Indo-China Himalayan region, Medicinal and Aromatic Plant Science and Biotechnology, 2010, 4 (1). 1-7. 

10.    Upendra Sharma, Pamita Bhandari, Neeraj Kumar, Bikram Singh Simultaneous Determination of Ten Sugars in Tinospora cordifolia by Ultrasonic Assisted Extraction and LC-ELSD. Chromatographia, 71, 633–638, 2010.

11.    Pamita Bhandari, Neeraj Kumar, Bikram Singh, Paramvir S. Ahuja. Online-HPLC-DPPH method for antioxidant activity of Picrorhiza kurroa and characterization of kutkoside by Ultra-Performance LC-electrospray ionization quadrupole time-of-flight mass spectrometry. Ind. J. Exp. Biol. 48, 323-328, 2010.

12.    Pamita Bhandari, Neeraj Kumar, Bikram Singh, Inderjeet Kaur. Dammarane triterpenoid saponins from Bacopa monnieri. Canadian Journal of Chemistry 87 (9), 1230-1234, 2009.

13.    Pamita Bhandari, Neeraj Kumar, Bikram Singh, Virendra Singh, Inderjeet Kaur. Silicabased monolithic column with evaporative light scattering detector for HPLC analysis of bacosides and apigenin in Bacopa monnieri. Journal of Separation Science, 32, 28122818, 2009.

14.    Neeraj kumar, Pamita Bhandari, Bikram singh, Shamsher S. Bari. Antioxidant Potential and Electrospray Ionization Mass Spectrometric Fingerprinting of Phenolic Constituents in Flowers of Rose Species: Rosa damascena, R. bourboniana and R. brunonii. Food and Chemical Toxicology 47(2), 361-367, 2009.

15.    Pamita Bhandari, Neeraj Kumar, Ajai P. Gupta, Bikram Singh, Vijay K. Kaul, Stability-indicating HPLC-PDA Method for Determination of Picrosides in Hepatoprotective Indian Herbal Preparations of Picrorhiza kurroa. Chromatographia, 69, 221-227, 2009.

16.    Neeraj Kumar, Pamita Bhadari, Ajai P. Gupta, Bikram Singh and Vijay K. Kaul. Reversed phase-HPLC for rapid determination of polyphenols in flowers of Rose species. Journal of Separation Science 31, 262-267, 2008.

17.    Pamita Bhandari, Neeraj Kumar, Bikram Singh, Vijay K Kaul Simultaneous determination of sugars and picrosides in Picrorhiza species using ultrasonic extraction and high-performance liquid chromatography with evaporative light scattering detection, Journal of Chromatography A, 1194, 257-261, 2008. 

18.         Vivek Sharma, Ajai P. Gupta, Pamita Bhandari, Raghbir C. Gupta, Bikram Singh, A validated and Densitometric HPTLC Method for the quantification of Withaferin-A and Withanolide-A in Different Plant parts of Two Morphotypes of Withania somnifera. Chromatographia, 66, 801–804, 2007.

19.    Martin Zehl, Ernst Pittenauer, Leopold Jirovetz, Pamita Bhandari, Bikram Singh, Vijay K. Kaul, Andreas Rizzi, and Guenter Allmaier, Multistage and Tandem Mass Spectrometry of Glycosylated Triterpenoid Saponins Isolated from Bacopa monnieri: Comparison of the Information Content Provided by Different Techniques, Analytical Chemistry, 79, 82148221, 2007.

20.    Pamita Bhandari, Neeraj Kumar, Ajai P. Gupta, Bikram Singh, Vijay K. Kaul, A rapid RP-HPTLC densitometry method for simultaneous determination of major flavonoids in important medicinal plants, Journal of Separation Science 30, 2092-2096, 2007.

21.    Neeraj Kumar, Pamita Bhandari, Bikram Singh and Vijay K. Kaul. Saponins and volatile constituents and from Lonicera japonica growing in Himalayan region of India. Natural Product Commnication, 06, 633-636, 2007.

22.    Pamita Bhandari, Neeraj Kumar, Bikram Singh, Vijay K Kaul, Cucurbitacins from Bacopa monnieri. Phytochemistry, 68, 1248-1254, 2007.  

23.    Neeraj Kumar, Pamita Bhadari, Bikram Singh, Ajai P. Gupta and Vijay K. Kaul. Steroidal alkaloids from Holarrhena antidysenterica. Chemical and Pharmaceutical Bulletin, 55 (6), 912-914, 2007.

24.    Pamita Bhandari, Ajai P. Gupta, Bikram Singh, Vijay K. Kaul, HPTLC Determination of Swertiamarin and Amarogentin in Swertia species from Western Himalayan Region. J. Planar Chromatography-Modren TLC, 19, 212-215, 2006.

25.    Pamita Bhandari, Neeraj Kumar, Bikram singh, Vijay K. Kaul. Micro-LC determination of swertiamarin in Swertia species and bacoside-A in Bacopa monnerie. Chromatographia, 64, 599-602, 2006.

26.    Neeraj Kumar, Bikram Singh, Pamita Bhandari, Ajai P. Gupta, Sanjay K. Uniyal, Vijay K. Kaul. Biflavonoids from Lonicera japonica. Phytochemistry, vol. 66, 3, 2740-2744, 2005.

27.    Pamita Bhandari, Neeraj Kumar, Bikram singh, Vijay K. Kaul. Bacosterol glycoside, A New 13, 14-Seco-steroid glycoside from Bacopa monneiri. Chemical and Pharmaceutical Bulletin, vol. 54, 2, 240-241, 2006. 

28.    Pamita Bhandari, Ajai P. Gupta, Bikram Singh, Vijay K. Kaul, Simultaneous densitometric determination of artemisinin, artemisinic acid and arteannuin-B in Artemisia annua using reversed- phase-thin-layer chromatography. Journal of Separation Science, 28, 2288-2292, 2005. 

 

 Papers presented in conferences: 14

 

 Technology Transferred (2020): 01 (M/s Nano Tech Chemical Brothers Pvt.          Ltd., Ludhiana-141112)

 

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