Natural Product Chemistry and Process Development
Scientist
Catalysis; C-H Activation; Natural Product Chemistry; Analytical Chemistry
01894 230426, Ext. 449; Mob. 09418792595
;
Ph.D.

 

Manjushree Pal Memorial Award for Best Oral Presentation from Ethanopharmacology Society of India, Kolkata (2017)

Thieme Chemistry Journal Award (2016)

Postdoc Fellowship KAIST, South Korea (2014)

D S Kothari Postdoc Fellowship (2012)

Fast Track Young Scientist project for three years (2012)

CSIR Senior Research Fellowship (2009)

CSIR Junior Research Fellowship (2007)

GATE (2007)

CSIR-NET (2006) 

 

Organic Synthesis & Catalysis

Transition Metal Catalysis for C-H Activation/Functionalization

Medicinal Chemistry

Synthesis of New Heterocycles (Quinoline, Indole, Furan) Derivatives as Potential Therapeutic Agents

Natural Product Chemistry

Characterization of New Molecules from Western Himalayan Plants

Chemical Profiling of Medicinal Plants

Scientific Validation of Traditional Knowledge on Himalayan Plants

 

Please Visit: https://sites.google.com/site/chactivationandphytochemistry/publications

 

Publications

 

Selected Publications

 

Organic Synthesis and Catalysis

 

85. Remote C-H Bond Activation/Transformations: A Continuous Growing Synthetic Tool; Part II.

R. Sharma, and U. Sharma*

Catalysis Reviews: Science and Engineering, 2018, DOI: 10.1080/01614940.2018.1474538. [Link].

 

84. C70 Fullerene-Catalyzed Metal-Free Photocatalytic ipso-Hydroxylation of Aryl Boronic Acids: Synthesis of Phenols 

I. Kumar, R. Sharma, R. Kumar, R. Kumar and U. Sharma*

Advanced Synthesis & Catalysis, 2018, 360, 2013. [Link]

 

83. Rhodium-Catalyzed Remote (C-8) alkylation of Quinolines with Activated and Unactivated Olefins: Mechanistic Study and Total Synthesis of EP4 Agonist 

R. Sharma, I. Kumar, R. Kumar and U. Sharma*

Advanced Synthesis & Catalysis, 2017, 359, 3022. [Link]

 

82. Metal-free synthesis of 2-substituted-3-(2-hydroxyaryl)quinolines and 4-(2-hydroxyaryl)acridines via benzyne chemistry

A. K. Dhiman, R. Kumar, R. Kumar,* and U. Sharma*

The Journal of Organic Chemistry, 2017, 82, 12307. [Link]

 

81. Regioselective Metal-free C(2)-H Arylation of Quinoline N-oxides with Aryldiazonium Salts/Anilines under Ambient Conditions.

R. Kumar, R. Kumar, A. K. Dhiman and U. Sharma*

Asian Journal of Organic Chemistry, 2017, 6, 1043. [Link] 

 

80. CuI nanoparticles as a recyclable heterogeneous catalyst for C-N bond formation reactions.

M. Kumar, V. Bhatt, O. S. Nayal, S. Sharma, V. Kumar, M. S. Thakur, N. Kumar, R. Bal,* B. Singh* and U. Sharma*

Catalysis Science & Technology, 2017, 7,  2857. [Link]

 

79. Synthesis of tertiary arylamines: Lewis acid-catalyzed direct reductive N-  alkylation of secondary amines with ketones through an alternative pathway.

O. S. Nayal, M. S. Thakur, V. Bhatt, M. Kumar, N. Kumar, B. Singh* and U. Sharma*

Chemical Communications, 2016, 52, 9648. [Link]

 

78. Catalyst and Solvent-Free alkylation of Quinoline N-oxides with Olefins: Direct Access to Quinoline Substituted α–Hydroxy Carboxylic Derivatives.

R. Kumar, I. Kumar, R. Sharma and U. Sharma*

Organic & Biomolecular Chemistry, 2016, 14, 2613. [Link]

 

77. Rh(III)-Catalyzed Dehydrogenative Coupling of Quinoline N-Oxides with Alkenes: N-Oxide as Traceless Directing Group for Remote C-H Activation.

R. Sharma, R. Kumar, I. Kumar and U. Sharma*

European Journal of Organic Chemistry, 2015, 7519. [Link]

 

76. Distant C-H Activation/Functionalization: A New Horizon of Selectivity beyond Proximity. 

R. Sharma, K. Thakur, R. Kumar, I. Kumar and U. Sharma*

Catalysis Reviews: Science and Engineering, 2015, 57(3), 345. [Link]

 

75. Orthogonal Selectivity with Cinnamic Acids in 3-Substituted Benzofuran Synthesis through C-H Olefination of Phenols.

S. Agasti, U. Sharma, T. Naveen and D. Maiti

Chemical Communications2015, 51, 5375.

 

74. Palladium-Catalyzed Annulation of Diarylamines with Olefins through C-H Activation: Direct Access to N-Arylindoles.

U. Sharma, R. Kancherla, N. Tagoti, S. Agasti amd D. Maiti

Angewandte Chemie International Edition, 2014, 53, 43.

 

73. Rh (III)- Catalyzed Traceless Coupling of Quinoline N-Oxides with Internal Diarylalkynes.

U. Sharma, Y. Park and S. Chang

Journal of Organic Chemistry, 2014, 79, 9899.

 

72. Palladium Ctalyzed Synthesis of Benzofurans and Coumarins from Phenols and Olefins.

U. Sharma, N. Tagoti, A. Maji, S. Manna and D. Maiti 

Angewandte Chemie International Edition, 2013, 52, 12669.

 

Natural Product Chemistry 

 

71. Comprehensive metabolomics study of traditionally Important Rumex Species found in Western Himalayan region.

R. Sharma, R. Jandrotia, B. Singh, U. Sharma* and D. Kumar*

Natural Product Communications, 2018, 13, 189.

 

70. Comprehensive metabolic profiling of Zanthoxylum armatum and Zanthoxylum acanthopodium leaves, bark, flowers and fruits using Ultra high performance liquid chromatography.

V. Bhatt, N. Kumar, U. Sharma and B. Singh*

Separation Science Plus, 2018, 1, 311-324. [Link]

 

69. Simultaneous quantification and identification of flavonoids, lignans, coumarin and amides in leaves of Zanthoxylum armatum using UPLC-DAD-ESI-QTOF–MS/MS.

V. Bhatt, S. Sharma, N. Kumar, U. Sharma and B. Singh

Journal of Pharmaceutical and Biomedical Analysis, 2017, 132, 46. [Link]

 

68. Cuspidate A, New Anti-Fungal Triterpenoid Saponin from Lepidagathis cuspidate

R. Rattan,* B. I. Fozdar, V. Gautam, R. Sharma,  D. Kumar* and U. Sharma

 

Natural Product Research, 2017, 31, 773. [Link]

 

67. Triterpenoid Saponins from Clematis graveolens and Evaluation of their Insecticidal Activities.

R. Rattan*, S. G. E. Reddy, S. K. Dolma, B. I. Fozdar, V. Gautam, R. Sharma and U. Sharma*

Natural Product Communications, 2015, 10(9), 1525.

 

66. Immunomodulatory Active Compounds from Tinospora cordifolia.

U. Sharma, M. Bala, N. Kumar, R. Munshi, S. Bhalerao and B. Singh

Journal of Ethnopharmacology, 2012, 141, 918.

 

65.New Furostanol Saponin and Phenyl Propanoid from Roots of Asparagus racemosus.

U. Sharma, N. Kumar, and B. Singh

Natural Product Communications2012, 7, 995.

 

Full List and Details: Complete Publications Details

 

Book Chapters

4. Direct Arylation via C-H activation.

U. Sharma, A. Modak, S. Maity, A. Maji and D. Maiti

Thomas CoIacot eds., Introduction to New Trends in Cross-Coupling: Theory and Applications. 2014. [Link]

 

3. In Vitro Studies on the Antioxidant/Antigenotoxic Potential of Aqueous Fraction from Anthocephalus cadamba Bark.

M. Chandel, U. Sharma, N. Kumar, B. Singh and S. Kaur

P.R. Sudhakaran et al. (eds.), Perspectives in Cancer Prevention-Translational Cancer Research, 2013, DOI 10.1007/978-81-322-1533-25. [Link]

 

*Corresponding Author

  

2. Benzothiazole Substituted Phthalimide Analogues as Potential Angiogenesis Inhibitors.

B. Singh, S. Chattergi, N. Kumar and U. Sharma.  

Ref. No. 0918 DEL 2011.

 

1. Palladium-Catalyzed Synthesis of Benzofurans and Coumarins from Phenols and Olefins.

U. Sharma, N. Tagoti, and D. Maiti.  

Status: Provisional. IPA No: 2012/Mum/2013.

 

 

 

Postdoc

Dr. Vinod Bhatt

 

Ph.D Fellow

 

Ms. Ritika Sharma 

Mr. Rakesh Kumar

Mr. Inder Kumar

 

Project Fellow

 

Mr. Ankit Dhiman

 

Prospective Team Members 


Ph.D and Postdoc positions available for self-motivated persons.

 

 

 

 

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